Position

Maître de Conférences  (MCU) / Ingénieur de Recherche

Coordonnées

Laboratoire AME2P
3 rue de la Chebarde
Campus Universitaire des Cézeaux
63170 Aubière CEDEX
Laurie.Isacco@uca.fr 

Programme de recherche


Programme A: Identification des adaptations physiologiques et énergétiques aux déficits énergétiques.  

Parcours


Master 2 APAS recherche - UFR STAPS Clermont-Ferrand
Doctorat - Laboratoire AME2P, Clermont-Ferrand
Post-doctorat - Université de Fribourg, Suisse
MCU - UFR STAPS de Besançon, Université Bourgogne Franche-Comté
Ingénieur de recherche - Laboratoire AME2P, Clermont-Ferrand

Thématique de recherche


Mes thématiques de recherche s'articulent autour de l'étude de la composition corporelle, du métabolisme énergétique et des réponses endocriniennes en lien avec l'exercice physique de différentes intensités, que ce soit dans un objectif de prévention primaire ou tertiaire de santé ou dans l'optimisation du suivi du sportif. Un intérêt tout particulier est porté à la population féminine.

Mots clés


Métabolisme énergétique, composition corporelle, hormones, niveau d'activité physique, femme

Responsabilités


Publications

Publications 2023

1: Moore H, Siroux J, Pereira B, Miguet M, Fillon A, Dionnet C, Julian V, Duclos M, Boirie Y, Finlayson G, Isacco L, Thivel D. The energy content of meals with a similar macronutrient distribution may have a greater impact on appetite sensations than food preferences in adolescents with obesity: A secondary analysis. Appetite. 2023 Sep 27;191:107063. doi: 10.1016/j.appet.2023.107063. Epub ahead of print. PMID: 37774844.

2: Siroux J, Pereira B, Fillon A, Moore H, Dionnet C, Julian V, Finlayson GS, Duclos M, Boirie Y, Isacco L, Thivel D. Higher energy flux may improve short-term appetite control in adolescents with obesity: the NEXT study. Br J Nutr. 2024 Jan 28;131(2):359-368. doi: 10.1017/S0007114523001824. Epub 2023 Aug 17. PMID: 37587692.

3: Fournier E, Łuszczki E, Isacco L, Chanséaume-Bussiere E, Gryson C, Chambrier C, Drapeau V, Chaput JP, Thivel D. Toward an Integrated Consideration of 24 h Movement Guidelines and Nutritional Recommendations. Nutrients. 2023 Apr 27;15(9):2109. doi: 10.3390/nu15092109. PMID: 37432285; PMCID: PMC10181315.

4: Isacco L, Lambert C, Siroux J, Boscaro A, Cardenoux C, Julian V, Duclos M, Boirie Y, Pereira B, Ennequin G, Thivel D. Weight loss does not affect the sit-to-stand metabolic cost in adolescents with obesity. Eur J Appl Physiol. 2023 Nov;123(11):2511-2523. doi: 10.1007/s00421-023-05247-8. Epub 2023 Jun 13. PMID: 37310434.

5: Pélissier L, Bagot S, Miles-Chan JL, Pereira B, Boirie Y, Duclos M, Dulloo A, Isacco L, Thivel D. Is dieting a risk for higher weight gain in normal-weight individual? A systematic review and meta-analysis. Br J Nutr. 2023 Oct 14;130(7):1190-1212. doi: 10.1017/S0007114523000132. Epub 2023 Jan 16. PMID: 36645258.

6: Fillon A, Pélissier L, Beaulieu K, Charlot K, Siroux J, Bagot S, Bailly M, Boscaro A, Finlayson G, Boirie Y, Duclos M, Isacco L, Pereira B, Julian V, Thivel D. Dietary- but not exercise-induced acute iso-energetic deficit result in short-term appetitive compensatory responses in adolescents with obesity. Appetite. 2023 Feb 1;181:106401. doi  10.1016/j.appet.2022.106401. Epub 2022 Dec 5. PMID: 36473580.

7: Ennequin G, Thivel D, Mourot L, Isacco L. Physically active men present a healthier cardiometabolic profile in response to a balanced meal compared to inactive men. Eur J Appl Physiol. 2023 Feb;123(2):283-297. doi: 10.1007/s00421-022-05067-2. Epub 2022 Oct 20. PMID: 36264326. 

8: Pélissier L, Ennequin G, Bagot S, Pereira B, Lachèze T, Duclos M, Thivel D, Miles-Chan J, Isacco L. Lightest weight-class athletes are at higher risk of weight regain: results from the French-Rapid Weight Loss Questionnaire. Phys Sportsmed. 2023 Apr;51(2):144-152. doi: 10.1080/00913847.2021.2014285. Epub 2022 Jan 5. PMID: 34875202.

Publications 2022


1: Fillon A, Pélissier L, Beaulieu K, Charlot K, Siroux J, Bagot S, Bailly M, Boscaro A, Finlayson G, Boirie Y, Duclos M, Isacco L, Pereira B, Julian V, Thivel D. Dietary- but not exercise-induced acute iso-energetic deficit result in short-term appetitive compensatory responses in adolescents with obesity. Appetite. 2023 Feb 1;181:106401. doi: 10.1016/j.appet.2022.106401. Epub 2022 Dec 5. PMID: 36473580.

2: Ennequin G, Thivel D, Mourot L, Isacco L. Physically active men present a healthier cardiometabolic profile in response to a balanced meal compared to inactive men. Eur J Appl Physiol. 2023 Feb;123(2):283-297. doi: 10.1007/s00421-022-05067-2. Epub 2022 Oct 20. PMID: 36264326. 

3: Kim J, Huang AY, Johnson SL, Lai J, Isacco L, Jeffries AM, Miller MB, Lodato MA, Walsh CA, Lee EA. Prevalence and mechanisms of somatic deletions in single human neurons during normal aging and in DNA repair disorders. Nat Commun. 2022 Oct 7;13(1):5918. doi: 10.1038/s41467-022-33642-w. PMID: 36207339; PMCID: PMC9546902.

4: Isacco L, Lambert C, Fearnbach N, Fillon A, Masurier J, Lowe M, Benson L, Duclos M, Pereira B, Boirie Y, Thivel D. Patterns of body weight change affect weight loss during a multidisciplinary intervention in adolescents with obesity. Obes Res Clin Pract. 2022 Sep-Oct;16(5):400-406. doi: 10.1016/j.orcp.2022.08.010. Epub 2022 Sep 7. PMID: 36088251.

5: Isacco L, Lazzer S, Pereira B, Fearnbach N, Montaurier C, Vermorel M, Rannou F, Boirie Y, Thivel D. Association of protein-energy partitioning with body weight and body composition changes in adolescents with severe obesity. Int J Obes (Lond). 2022 Nov;46(11):2021-2028. doi: 10.1038/s41366-022-01218-9. Epub 2022 Aug 31. PMID: 36045150.

6: Guirado T, Bourdier P, Pereira B, Le Roux E, Bergouignan A, Birat A, Isacco L, Thivel D, Duclos M, Metz L. Metabolic profile in women differs between high versus low energy spenders during a low intensity exercise on a cycle-desk. Sci Rep. 2022 Jun 15;12(1):9928. doi: 10.1038/s41598-022-14002-6. PMID: 35705612; PMCID: PMC9200836.

7: Isacco L, Gimenez P, Ennequin G, Mourot L, Grosprêtre S. Cardiometabolic and neuromuscular analyses of the sit-to-stand transition to question its role in reducing sedentary patterns. Eur J Appl Physiol. 2022 Jul;122(7):1727-1739. doi: 10.1007/s00421-022-04954-y. Epub 2022 Apr 27. PMID: 35474143.

8: Pélissier L, Ennequin G, Bagot S, Pereira B, Lachèze T, Duclos M, Thivel D, Miles-Chan J, Isacco L. Lightest weight-class athletes are at higher risk of weight regain: results from the French-Rapid Weight Loss Questionnaire. Phys Sportsmed. 2023 Apr;51(2):144-152. doi: 10.1080/00913847.2021.2014285. Epub 2022 Jan 5. PMID: 34875202.

9: Pélissier L, Julian V, Beaulieu K, Siroux J, Boscaro A, Fillon A, Finlayson G, Duclos M, Boirie Y, Pereira B, Isacco L, Thivel D. Effect of acute dietary-versus combined dietary and exercise-induced energy deficits on subsequent energy intake, appetite and food reward in adolescents with obesity. Physiol Behav. 2022 Feb 1;244:113650. doi: 10.1016/j.physbeh.2021.113650. Epub 2021 Nov 17. PMID: 34798127.

10: Metz L, Isacco L, Redman LM. Effect of oral contraceptives on energy balance in women: A review of current knowledge and potential cellular mechanisms. Metabolism. 2022 Jan;126:154919. doi: 10.1016/j.metabol.2021.154919. Epub 2021 Oct 27. PMID: 34715118.

11: Boisseau N, Isacco L. Substrate metabolism during exercise: Sexual dimorphism and women's specificities. Eur J Sport Sci. 2022 May;22(5):672-683. doi: 10.1080/17461391.2021.1943713. Epub 2021 Jul 11. PMID: 34134602.

Publications 2021

Grosprêtre S, Marusic U, Gimenez P, Ennequin G, Mourot L, Isacco L. Stand up to excite the spine: neuromuscular, autonomic, and cardiometabolic responses during motor imagery in standing versus sitting posture (2021). Frontiers in physiology.12: 762452.
D’Alleva M, Gonnelli F, Vaccari F, Boirie Y, Montaurier C, Thivel D, Isacco L, Vermorel M, Lazzer S. Energy cost of walking and body composition changes during a 9-month multidisciplinary weight reduction program and 4-month follow-up in adolescents with obesity (2021). Appl Physiol Nutr Metab. In press.
Boisseau N, Isacco L. Substrate metabolism during exercise: sexual dimorphism and women’s specificities (2021). Eur J Sport Sci. In press.
Isacco L, Ennequin G, Boisseau N. Influence of the different hormonal status changes during their life on fat mass localisation in women: a narrative review (2021). Arch Physiol Biochem. In press.
Calonne J, Fares EJ, Montani JP, Schutz Y, Dulloo A, Isacco L. Dynamics of fat oxidation from sitting at rest to light exercise in inactive young humans (2021). Metabolites. 11(6): 334.
Charles M, Thivel D, Verney J, Isacco L, Husu P, Vähä-ypyä H, Vasankari T, Tardieu M, Fillon A, Genin P, Larras B, Chabanas B, pereira B, Duclos M. Reliability and validity of the ONAPS physical activity questionnaire in assessing physical activity and sedentary behavior in French adults (2021). Int J Environ Res Public Health. 18(11): 5643.
Grosprêtre S, Ennequin G, Peseux S, Isacco L. Feasability and acceptability of “active” classroom workstations among French university students and lecturers: a pilot study. (2021). BMC Public Health. 21(1): 1001.
Nutrients. 13(4): 1051.
Thivel D, Metz L, Julian V, Isacco L, Verney J, Ennequin G, Charlot K, Beaulieu K, Finlayson G, King JA. Diet- but not exercise-induced iso-energetic deficit induces compensatory appetitive responses (2021). Eur J Clin Nutr. 75(10): 1425-1432.
Metz L, Isacco L, Beaulieu K, Fearnbach SN, Pereira B, Thivel D, Duclos M. Cold-Water Effects on Energy Balance in Healthy Women During Aqua-Cycling (2021). Int J Sport Nutr Exerc Metab. 31(3):236-243.
Khammassi M, Isacco L, Pereira B, Damaso AR, Matlosz P, Maruszczak K, Weghuber D, Dutheil F, Duclos M, Boirie Y, Julian V, Thivel D. Cardiometabolic efficacy of multidisciplinary weight loss interventions is not altered in adolescents with obesity initially diagnosed or with a persistent metabolic syndrome (2021). Nutr Res. 86: 79-87.

Publications 2020

Miles-Chan JL, Isacco L. Weight cycling practices in sport: A risk factor for later obesity? (2020). Obes Rev. 22 Suppl 2: e13188.
Julian V, Isacco L, Khammassi M, Fillon A, Miguet M, Dutheil F, Courteix D, Zak M, Bicki J, Głuszek S, Duclos M, Boirie Y, Pereira B, Thivel D. Appetite Control Might not Be Improved after Weight Loss in Adolescents with Obesity, Despite Non-Persistent Metabolic Syndrome (2020). Nutrients. 12(12): 3885.
Isacco L, Ennequin G, Boisseau N. Effect of Fat Mass Localization on Fat Oxidation During Endurance Exercise in Women (2020). Front Physiol. 11: 585137.
Roche J, Corgosinho FC, Isacco L, Scheuermaier K, Pereira B, Gillet V, Moreira GA, Pradella-Hallinan M, Tufik S, de Mello MT, Mougin F, Dâmaso AR, Thivel D. A multidisciplinary weight loss intervention in obese adolescents with and without sleep-disordered breathing improves cardiometabolic health, whether SDB was normalized or not. Sleep Med. 75: 225-235.
Mourot L, Fornasiero A, Rakobowchuk M, Isacco L, Brighenti A, Stella F, Zignoli A, Pelligrini B, Tarperi C, Schena F (2020). Post-exercise hypotension and reduced cardiac baroreflex after half-marathon run: in men, but not in women. Int J Environ Res Public Health. 17(17): 6337
Roche J, Corgosinho FC, Damaso AR, Isacco L, Miguet M, Fillon A, Guyon A, Moreira G.A, Pradella-Hallinan M, Tufik S, de Mello MT, Gillet V, Pereira B, Duclos M, Boirie Y, Masurier J, Franco P, Thivel D, Mougin F (2020). Sleep-disordered breathing in adolescents with obesity: When does it start to affect cardiometabolic health? Nutrition, Metabolism & Cardiovascular Disease. 30(4): 683-693.
Roche J, Isacco L, Masurier J, Pereira B, Mougin F, Chaput JP, Thivel D (2020). Are obstructive sleep apnea and sleep improved in response to multidisciplinary weight loss interventions in adolescents with obesity? A systematic review and meta-analysis. Int J Obes. 44(4): 753-770.
Isacco L, Degoutte F, Ennequin G, Pereira B, Thivel D, Filaire E (2020). Rapid weight loss influences the physical, psychological and biological responses during a simulated competition in national judo athletes. Eur J Sport Sci. 20(5): 580-591.

Publications précédentes

https://pubmed.ncbi.nlm.nih.gov/?term=isacco+l&filter=years.2008-2019&sort=date