Professeur des Universités (PU)


Laboratoire AME2P
3 rue de la Chebarde
Campus Universitaire des Cézeaux
63170 Aubière CEDEX

Programme de recherche

Programme B. Pathologies métaboliques et mesures hygiéno-diététiques : adaptations physiologiques et fonctionnelles
Programme C. Performance, croissance et sexe



Nathalie Boisseau is Professor in Exercise Physiology at the Sport Sciences Faculty, University of Clermont Auvergne (UCA-Clermont Ferrand, France). She is a member of the research team called “Metabolic adaptations to exercise in physiological and pathological conditions (AME2P)” where she manages a program called “Metabolic disease, nutrition, and physical activities: physiological and functional adaptations”. She also manages the Master's degree on "Physical Activity and Health" at UCA-Clermont-Ferrand. After her PhD in Exercise Physiology at Rennes University, she worked as a postdoctoral fellows on Exercise, Nutrition and Health at Oxford University, UK. She has been invited to give many lectures at meetings and she is also implicated in the students’ education and training in Sport Sciences at UCA-Clermont Ferrand. Professor Nathalie Boisseau is a member of several national and international sport science societies. She has published more than 75 peer-reviewed original articles in international peer-reviewed journals, three books (“Biochemistry of Physical Activities and Sports”, “Nutrition and Physical Activities” and “Women and Exercise Physiology”), and 15 book chapters.


Madame Nathalie Boisseau est professeur en physiologie du sport à l'UFR STAPS de Clermont-Ferrand. Elle est membre du laboratoire "Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques (AME2P)" où elle dirige un programme de recherche intitulé « Pathologies métaboliques et mesures hygiéno-diététiques : adaptations physiologiques et fonctionnelles ». Elle dirige également la mention du Master "Activité Physique Adaptée et Santé" au sein de l'UFR STAPS de Clermont-Ferrand. Elle a une formation en physiologie de l'exercice avec un doctorat obtenu à l'Université de Rennes 2, et un post-doctorat réalisé à l'Université d'Oxford au Royaume-Uni. Elle contribue à de nombreuses conférences invitées, congrès, et participe à la formation d’étudiants, majoritairement sur l'Université Clermont Auvergne. Enfin, Madame le Professeur Nathalie Boisseau est membre de plusieurs sociétés savantes nationales et internationales dans le domaine de l'activité physique et de la nutrition. Elle a publié plus de 75 articles originaux, trois ouvrages et réalisé plus de 15 chapitres au sein d'ouvrages collectifs.

Thématique de recherche

Currently, her research work is focused on metabolic and hormonal adaptations to exercise, particularly the effect of different exercise modalities on body composition and health. In this context, she is interested also in understanding the influence of the hormonal and nutritional status. Professor Nathalie Boisseau is involved in basic and clinical research studies in the field of energy metabolism, particularly its regulation by exercise and diet, in healthy individuals and in patients with metabolic disorders and also in animal models.

Elle travaille plus précisément sur les adaptations du métabolisme énergétique à l'exercice et s’intéresse particulièrement aux effets des modalités d’effort sur la composition corporelle et la santé. L’état nutritionnel et l’influence du statut hormonal sont également des centres d’intérêt. Ses travaux, réalisés sur modèle humain ou animal, s’appliquent à des populations saines ou souffrant de pathologies métaboliques.

Mots clés

Key words: overweight/obesity, physical activity program, body composition, age, sex, nutrition.
Mots clés : surpoids/obésité, modalités d’exercice, composition corporelle, âge, sexe, nutrition.


Responsable Master 2 Activité Physique Adaptée et Santé
Elue au Bureau de L'Ecole Doctorale SVSAE
Ancienne Directrice Laboratoire AME2P


Publications 2023

  1. Couvert A, Goumy L, Maillard F, Esbrat A, Lanchais K, Saugrain C, Verdier C, Doré E, Chevarin C, Adjtoutah D, Morel C, Pereira B, Martin V, Lancha Junior AH, Barnich N, Chassaing B, Rance M, Boisseau N. (2023) « Effects of a cycling vs. running HIIT program on fat mass loss and gut microbiota composition in men with overweight/obesity. Med Sci Sports Exerc, in press. IF : 6.289.
  2. Haguet Q, Le Joubioux F, Chavanelle V, Groult H, Schoonjans N, Langhi C, Michaux A, Otero YF, Boisseau N, Peltier SL, Sirvent P, Maugard T (2023). « Enzymatic studies of the inhibition of α-amylase, α-glucosidase, and pancreatic lipase, by a formulation of five plant extracts ». International Journal of Molecular Sciences (IJMS),11;24(4):3652. IF : 6.02.
  3. Igonin PH, Cognasse F, Gonzalo P, Philippot R, Rogowski I, Sabot T, Boisseau N*, Martin C* (2023). « Comparison of sprint velocity, change of direction velocity, and repeated sprint ability throughout the menstrual cycle of sub-elite women football players ». Science and Medecine in Footall, in press, IF : 3.4.
  4. Piponnier E, Ishikawa M, Kunimasa Y, Sano K, Jagot K, Boisseau N, Kurihara T, Martin V. (2023). « Quantification of extramyocellular lipids and intramuscular fat from muscle echo intensity in lower limb muscles: a comparison of four ultrasound devices against magnetic resonance spectroscopy ». Sensors., 2;23(11):5282. IF: 3.847.

Publications 2022

  1. Aparecido, J., C. S. Frientes, G. L. Martins, G. C. Santos, J. D. Alves Silva, P. S. Rogeri, R. S. Pires, T. S. Amorim, T. da Silva, T. E. Santo, N. Boisseau, A. H. Lancha Jr. and M. L. Marquezi (2022). "Training Mode Compari-sons on Cardiorespiratory, Body Composition and Metabolic Profile Adaptations in Reproductive-Age Women: A Systemic Review and Meta-Analysis." Obesities.
  2. Barasinski, C., C. Zaros, J. Bercherie, J. Y. Bernard, N. Boisseau, A. Camier, C. Chanal, B. Doray, R. Dugravier, A. Evrard, A. S. Ficheux, R. Garlantézec, M. Kadawathagedara, A. Laurent-Vannier, M. Lecorguillé, C. Marie, F. Molénat, F. Pelé, B. P. de Villepin, V. Rigourd, M. Rousseau, L. Storme, S. Weiss, C. Salinier and R. Béranger (2022). "Intervention during the Perinatal Period: Synthesis of the Clinical Practice Guidelines from the French National College of Midwives." J Midwifery Womens Health 67 Suppl 1: S2-S16.
  3. Boisseau, N. (2022). "Physical Activity During the Perinatal Period: Guidelines for Interventions During the Perinatal Period from the French National College of Midwives." J Midwifery Womens Health 67 Suppl 1: S158-S171.
  4. Boisseau, N. and L. Isacco (2022). "Substrate metabolism during exercise: Sexual dimorphism and women's specificities." Eur J Sport Sci 22(5): 672-683.
  5. Boisseau, N., N. Barnich and C. Koechlin-Ramonatxo (2022). "The Nutrition-Microbiota-Physical Activity Triad: An Inspiring New Concept for Health and Sports Performance." Nutrients 14(5).
  6. Dupuit, M., M. Rance, C. Morel, P. Bouillon, A. Boscaro, V. Martin, E. Vazeille, N. Barnich, B. Chassaing and N. Boisseau (2022). "Effect of Concurrent Training on Body Composition and Gut Microbiota in Postmenopausal Women with Overweight or Obesity." Med Sci Sports Exerc 54(3): 517-529.
  7. Igonin, P. H., I. Rogowski, N. Boisseau and C. Martin (2022). "Impact of the Menstrual Cycle Phases on the Movement Patterns of Sub-Elite Women Soccer Players during Competitive Matches." Int J Environ Res Public Health 19(8).
  8. Plissonneau, C., A. Sivignon, B. Chassaing, F. Capel, V. Martin, M. Etienne, I. Wawrzyniak, P. Chausse, F. Dutheil, G. Mairesse, G. Chesneau, N. Boisseau and N. Barnich (2022). "Beneficial Effects of Linseed Supplementation on Gut Mucosa-Associated Microbiota in a Physically Active Mouse Model of Crohn's Disease." Int J Mol Sci 23(11).
  9. Sirvent, P., V. Chavanelle, Y. F. Otero, M. Bargetto, F. Le Joubioux, N. Boisseau, T. Maugard, M. Cazaubiel, B. Pereira, B. Guigas, S. Hadjadj, S. L. Peltier, A. Marette and J. M. Bard (2022). "TOTUM-63, a plant-based polyphenol-rich extract, improves glycaemic control in subjects with prediabetes or early stage newly-diagnosed type 2 diabetes in a randomized, double-blind, placebo-controlled trial." Diabetes Obes Metab 24(12): 2331-2340.

Publications 2021

Boisseau, N. and L. Isacco (2021). "Substrate metabolism during exercise: sexual dimorphism and women's specificities." Eur J Sport Sci: 1-21. IF: 4.05

Chavanelle, V., Y. F. Otero, F. Le Joubioux, D. Ripoche, M. Bargetto, A.  Vluggens, C. Montaurier, G. Pickering, G. Ducheix, C. Dubray, C. Dualé,  S. Boulliau, N. Macian, G. Marceau, V. Sapin, F. Dutheil, B. Guigas, T.  Maugard, N. Boisseau, M. Cazaubiel, S. L. Peltier and P. Sirvent  (2021). "Effects of Totum-63 on glucose homeostasis and postprandial  glycemia: a translational study." Am J Physiol Endocrinol Metab320(6): E1119-E1137. IF: 3.99

Dupuit, M., V. Chavanelle, B. Chassaing, F. Perriere, M. Etienne, C.  Plissonneau, A. Boscaro, N. Barnich, V. Pialoux, T. Maugard, F. Le  Joubioux, S. Peltier, P. Sirvent, Y. F. Otero and N. Boisseau (2021).  "The TOTUM-63 Supplement and High-Intensity Interval Training  Combination Limits Weight Gain, Improves Glycemic Control, and  Influences the Composition of Gut Mucosa-Associated Bacteria in Rats on a  High Fat Diet." Nutrients13(5). IF: 5.719

Dupuit, M., M. Rance, C. Morel, P. Bouillon, A. Boscaro, V. Martin, E.  Vazeille, N. Barnich, B. Chassaing and N. Boisseau (2021). "Impact of  Concurrent Training on Body Composition and Gut Microbiota in  Postmenopausal Women with Overweight or Obesity." Med Sci Sports Exerc. IF: 4.029

Groussard, C., C. Plissonneau, L. Josset, F. Capel, M. Mura, E. Gouraud,  G. Mairesse, G. Chesneau, N. Barnich, V. Pialoux and N. Boisseau  (2021). "Beneficial Effects of High Intensity Interval Training and/or  Linseed Oil Supplementation to Limit Obesity-Induced Oxidative Stress in  High Fat Diet-Fed Rats." Nutrients13(10). IF: 5.719

Isacco, L., G. Ennequin and N. Boisseau (2021). "Influence of the  different hormonal status changes during their life on fat mass  localisation in women: a narrative review." Arch Physiol Biochem: 1-6. IF: 4.076

Plissonneau, C., F. Capel, B. Chassaing, M. Dupuit, F. Maillard, I.  Wawrzyniak, L. Combaret, F. Dutheil, M. Etienne, G. Mairesse, G.  Chesneau, N. Barnich and N. Boisseau (2021). "High-Intensity Interval  Training and α-Linolenic Acid Supplementation Improve DHA Conversion and  Increase the Abundance of Gut Mucosa-Associated." Nutrients13(3).  IF: 5.719

Publications 2020

Dupuit, M., A. Boscaro, A. Bonnet, P. Bouillon, P. Bruno, C. Morel, M.  Rance and N. Boisseau (2020). "Acute metabolic responses after  continuous or interval exercise in post-menopausal women with overweight  or obesity." Scand J Med Sci Sports30(12): 2352-2363. IF: 4.221

Dupuit, M., F. Maillard, B. Pereira, M. L. Marquezi, A. H. Lancha and N.  Boisseau (2020). "Effect of high intensity interval training on body  composition in women before and after menopause: a meta-analysis." Exp Physiol105(9): 1470-1490. IF: 2.969

Dupuit, M., M. Rance, C. Morel, P. Bouillon, B. Pereira, A. Bonnet, F. Maillard, M. Duclos and N. Boisseau (2020). "Moderate-Intensity  Continuous Training or High-Intensity Interval Training with or without  Resistance Training for Altering Body Composition in Postmenopausal  Women." Med Sci Sports Exerc52(3): 736-745. IF: 5.411

Ennequin, G., K. Caillaud, V. Chavanelle, A. Teixeira, M. Etienne, X.  Li, N. Boisseau and P. Sirvent (2020). "Neuregulin 1 treatment improves  glucose tolerance in diabetic db/db mice, but not in healthy mice." Arch Physiol Biochem126(4): 320-325. IF: 4.076

Gay, C., C. Guiguet-Auclair, N. Coste, N. Boisseau, L. Gerbaud, B.  Pereira and E. Coudeyre (2020). "Limited effect of a self-management  exercise program added to spa therapy for increasing physical activity  in patients with knee osteoarthritis: A quasi-randomized controlled  trial." Ann Phys Rehabil Med63(3): 181-188. IF: 4.919

Isacco, L., G. Ennequin and N. Boisseau (2020). "Effect of Fat Mass  Localization on Fat Oxidation During Endurance Exercise in Women." Front Physiol11: 585137. IF : 4.566

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